Author

C. Botte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Y. Yamaryo· 2 shared A. Flammersfeld· 1 shared A. Flieger· 1 shared A. MILLET· 1 shared A. Panyot· 1 shared A. Vantaux· 1 shared B. Witkowski· 1 shared C. Gonzales Pietro· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

Y. Yamaryo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers

K. Gharzeddine, C. Gonzales Pietro, M. Malier, C. Hennot, R. Grespan, Y. Yamaryo, C. Botte, F. Thomas, M. H. Laverriere, E. Girard, G. Roth, A. MILLET

This study shows that blocking CSF-1R in tumor-associated macrophages alters their metabolism, enhancing sensitivity to 5-fluorouracil in colorectal cancer.

bioRxiv · Feb 22, 2024 · PreprintImmunology

Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites

K. Ashraf, S. Tajeri, C.-S. Arnold, N. Amanzougaghene, J.-F. Franetich, A. Vantaux, V. Soulard, M. Bordessoulles, G. Cazals, T. Bousema, G.-J. van Gemert, R. Le Grand, N. Dereuddre-Bosquet, J.-C. Barale, B. Witkowski, , D. Mazier

This study shows that Artemisia infusions inhibit Plasmodium stages without artemisinin, suggesting potential for new antimalarial compounds.

bioRxiv · Aug 10, 2021Microbiology

A patatin-like phospholipase is crucial for gametocyte induction in the malaria parasite Plasmodium falciparum

A. Flammersfeld, A. Panyot, Y. Yamaryo, P. Aurass, J. M. Pryborski, A. Flieger, C. Botte, G. Pradel

This study shows that PNPLA1 deficiency in Plasmodium falciparum impairs gametocyte induction by altering phospholipid levels and gene expression related to sexual commitment.

bioRxiv · Jul 11, 2019Cell Biology