Author

K. Gharzeddine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Millet· 2 shared A. Ortega· 1 shared C. Valotteau· 1 shared F. Lafont· 1 shared F. Rico· 1 shared F. THOMAS· 1 shared G. ROTH· 1 shared J. Lopez-Alonso· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

A. Millet

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiophysicsbioRxivNov 29, 2022

Coupled mechanical mapping and interference contrast microscopy reveal viscoelastic and adhesion hallmarks of monocytes differentiation into macrophages

M. Eroles, J. Lopez-Alonso, A. Ortega…·F. Rico

This study uses mechanical and adhesion imaging to show that macrophages become stiffer and more adhesive than monocytes during differentiation.

DOI 10.1039/d3nr00757j

𝕏 PostBluesky

Cell BiologybioRxivOct 15, 2020

Hypoxia Drives Dihydropyrimidine Dehydrogenase Expression in Macrophages and Confers Chemoresistance in Colorectal Cancer

M. MALIER, M. COURT, K. GHARZEDDINE…·A. MILLET

This study identifies hypoxia-driven DPD expression in tumor-associated macrophages as a mechanism of 5-FU chemoresistance in colorectal cancer, with species-specific differences observed between human and mouse models.

DOI 10.1158/0008-5472.can-21-1572

𝕏 PostBluesky