An environmentally ultrasensitive fluorine probe to resolve protein conformational ensembles by 19F NMR and cryo-EM
Y. Huang, K. D. Reddy, C. Bracken, B. Qiu, W. Zhan, D. Eliezer, O. Boudker
This paper introduces a fluorine probe that enhances 19F NMR sensitivity for studying protein conformational changes, validated by cryo-EM structural analysis.
bioRxiv · Mar 29, 2022 · PreprintBiophysics