Author

C. Bradfield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Clements· 1 shared A. Huseth· 1 shared B. Sanchez-Sedillo· 1 shared C. D. Rubinstein· 1 shared D. Amezian· 1 shared D. De Nardo· 1 shared E. Latz· 1 shared G. Pegoraro· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEcology

A. Clements

Mutual co-authors in cluster

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3 papers

Recent·Most cited

The Circadian Clock is Disrupted in Pancreatic Cancer

P. B. Schwartz, M. Nukaya, M. Berres, C. D. Rubinstein, G. Wu, J. Hogenesch, C. Bradfield, S. Ronnekleiv-Kelly

This paper demonstrates circadian clock disruption in human pancreatic cancer using bioinformatics and genetic models, showing dysregulated clock genes and accelerated cancer progression.

bioRxiv · Nov 1, 2022Cancer Biology

IRAK1-mediated coincidence detection of microbial signals licenses inflammasome activation

S. J. Vayttaden, M. Smelkinson, O. Ernst, R. J. Carlson, J. Sun, C. Bradfield, M. G. Dorrington, J. Liang, N. Bouladoux, R. A. Gottschalk, K.-S. Oh, G. Pegoraro, S. Ganesan, D. De Nardo, E. Latz, , I. D. C. Fraser

This study identifies IRAK1-mediated supramolecular organizing centers that coordinate multiple immune pathways to license inflammasome activation in response to microbial signals.

bioRxiv · Dec 26, 2019 · PreprintImmunology

Agricultural fungicides inadvertently influence the fitness of Colorado potato beetles, Leptinotarsa decemlineata, and their susceptibility to insecticides

J. Clements, S. Schoville, A. Clements, D. Amezian, T. Davis, B. Sanchez-Sedillo, C. Bradfield, A. Huseth, R. Groves

This study investigates how fungicide exposure affects the insecticide resistance of Colorado potato beetles by examining phenotypic and molecular detoxification responses.

bioRxiv · Mar 22, 2018Ecology