Author

A. Clements

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4 Bioengineering· 1 Ecology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

J. Sanchez-Garrido· 3 shared F. Morecchiato· 2 shared G. Frankel· 2 shared G. M. Rossolini· 2 shared J. Watson· 2 shared S. David· 2 shared S. Mostowy· 2 shared T. Giani· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

J. Sanchez-Garrido

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Widespread emergence of OmpK36 loop 3 insertions among multidrug-resistant clones of Klebsiella pneumoniae

S. David, J. Wong, J. Sanchez-Garrido, J. Kwong, W. W. Low, F. Morecchiato, T. Giani, G. M. Rossolini, S. Brett, A. Clements, K. Beis, D. Aanensen, G. Frankel

This study identifies and characterizes OmpK36 loop 3 insertions in Klebsiella pneumoniae, showing their role in carbapenem resistance and clonal spread across different geographic regions.

bioRxiv · Feb 7, 2022Microbiology

Recurrent emergence of carbapenem resistance in Klebsiella pneumoniae mediated by an inhibitory ompK36 mRNA secondary structure

J. L. C. Wong, S. David, J. Sanchez-Garrido, J. Z. Woo, W. W. Low, F. Morecchiato, T. Giani, G. M. Rossolini, S. J. Brett, A. Clements, D. M. Aanensen, S. Rouskin, G. Frankel

This study identifies a synonymous mutation in ompK36 that increases carbapenem resistance in Klebsiella pneumoniae by causing translational suppression.

bioRxiv · Jan 5, 2022Microbiology

Therapeutic downregulation of neuronal PAS domain 2 (Npas2) promotes surgical skin wound healing

Y. Shibuya, A. Hokugo, H. Okawa, T. Kondo, D. Khalil, L. Wang, Y. Roca, A. Clements, H. Sasaki, E. Berry, I. Nishimura, R. Jarrahy

This study identifies a compound, Dwn1, that downregulates Npas2 and accelerates wound healing with reduced scarring in mice.

bioRxiv · Nov 29, 2021Bioengineering

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

V. Torraca, M. Kaforou, J. Watson, G. M. Duggan, H. Guerrero-Gutierrez, S. Krokowski, M. Hollinshead, T. B. Clarke, R. J. Mostowy, G. S. Tomlinson, V. Sancho-Shimizu, A. Clements, S. Mostowy

This paper shows that Shigella sonnei's O-antigen mediates neutrophil tolerance and increases dysentery incidence in zebrafish, suggesting O-antigen as a therapeutic target.

PLOS Pathogens · Dec 12, 2019Peer-reviewedMicrobiology

Shigella sonnei O-antigen inhibits internalisation, vacuole escape and inflammasome activation

J. Watson, J. Sanchez-Garrido, P. Goddard, V. Torraca, S. Mostowy, A. R. Shenoy, A. Clements

This study shows that S. sonnei's O-antigen reduces macrophage uptake and vacuole escape, leading to less pyroptosis compared to S. flexneri.

bioRxiv · Oct 9, 2019 · PreprintMicrobiology

Agricultural fungicides inadvertently influence the fitness of Colorado potato beetles, Leptinotarsa decemlineata, and their susceptibility to insecticides

J. Clements, S. Schoville, A. Clements, D. Amezian, T. Davis, B. Sanchez-Sedillo, C. Bradfield, A. Huseth, R. Groves

This study investigates how fungicide exposure affects the insecticide resistance of Colorado potato beetles by examining phenotypic and molecular detoxification responses.

bioRxiv · Mar 22, 2018Ecology