PathologybioRxiv
RASSF1A independence and early Galectin-1 upregulation in PIK3CA induced hepatocarcinogenesis: new therapeutic venues
A. Scheiter, K. Evert, L. Reibenspies…·K. Utpatel
This study shows that PIK3CA mutations drive hepatocarcinogenesis independently of RASSF1A status, with early Galectin-1 upregulation and synergistic therapeutic effects of PIK3CA and Galectin-1 inhibitors.
DOI 10.1002/1878-0261.13135