Author

F. Dombrowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Cigliano· 2 shared A. Coluccio· 1 shared A. Scheiter· 1 shared A. Teufel· 1 shared B. Sun· 1 shared C. Brochhausen· 1 shared C. Metzendorf· 1 shared D. Calvisi· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPathology

A. Cigliano

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2 papers

Recent·Most cited

RASSF1A independence and early Galectin-1 upregulation in PIK3CA induced hepatocarcinogenesis: new therapeutic venues

A. Scheiter, K. Evert, L. Reibenspies, A. Cigliano, K. Annweiler, K. Mueller, L.-M.-G. Poehmerer, T. Itzel, S. Materna-Reichelt, A. Coluccio, K. Honarnejad, A. Teufel, C. Brochhausen, F. Dombrowski, X. Chen, , K. Utpatel

This study shows that PIK3CA mutations drive hepatocarcinogenesis independently of RASSF1A status, with early Galectin-1 upregulation and synergistic therapeutic effects of PIK3CA and Galectin-1 inhibitors.

bioRxiv · Jun 15, 2021Pathology

Transcriptomic and Proteomic analysis of clear cell foci (CCF) in the human non-cirrhotic liver identifies several differentially expressed genes and proteins with functions in cancer cell biology and glycogen metabolism.

C. Metzendorf, K. Wineberger, J. Rausch, A. Cigliano, D. F. Calvisi, K. Peters, B. Sun, D. Mennerich, T. Kietzmann, F. Dombrowski, S. Ribback

The paper identifies differentially expressed genes and proteins in liver clear cell foci (CCF) and finds that reduced expression of STBD1 and USP28 is unlikely to explain glycogen overload.

bioRxiv · Feb 10, 2020Cancer Biology