Author

A. Teufel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Research Focus:sequence-to-function modeling· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Cigliano· 1 shared A. Coluccio· 1 shared A. Scheiter· 1 shared C. Brochhausen· 1 shared C. O. Wilke· 1 shared D. Calvisi· 1 shared E. L. Jackson· 1 shared F. Dombrowski· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPathology

A. Cigliano

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Author profile →

2 papers

Recent·Most cited

RASSF1A independence and early Galectin-1 upregulation in PIK3CA induced hepatocarcinogenesis: new therapeutic venues

A. Scheiter, K. Evert, L. Reibenspies, A. Cigliano, K. Annweiler, K. Mueller, L.-M.-G. Poehmerer, T. Itzel, S. Materna-Reichelt, A. Coluccio, K. Honarnejad, A. Teufel, C. Brochhausen, F. Dombrowski, X. Chen, , K. Utpatel

This study shows that PIK3CA mutations drive hepatocarcinogenesis independently of RASSF1A status, with early Galectin-1 upregulation and synergistic therapeutic effects of PIK3CA and Galectin-1 inhibitors.

bioRxiv · Jun 15, 2021Pathology

Beyond thermodynamic constraints: Evolutionary sampling generates realistic protein sequence variation

Q. Jiang, A. Teufel, E. L. Jackson, C. O. Wilke

This study shows that evolutionary simulation generates more realistic protein sequence variation than current design methods, highlighting the need for realistic sampling schemes.

bioRxiv · Jan 25, 2018Evolutionary Biology