C. Burballa

The ulcerative colitis associated gene FUT8 regulates the quantity and quality of secreted mucins

This study shows that FUT8 regulates mucin secretion and viscoelastic properties, linking its dysfunction to ulcerative colitis pathogenesis.

Global gene-expression analysis reveals the molecular processes underlying ClC-5 loss-of-function in novel Dent Disease 1 cellular models

The paper uses human proximal tubule cell models to study gene expression changes caused by ClC-5 loss-of-function mutations, revealing distinct molecular pathways affected by different mutations.

Palmitoylation of KChIP3 controls baseline mucin secretion

This study shows that palmitoylation of KChIP3 by zDHHC3 or zDHHC4 is required for its recruitment to mucin granules, thereby regulating baseline mucin secretion.