Cancer BiologybioRxiv
Interleukin-12 elicits a non-canonical response in B16 melanoma cells to enhance survival
C. Byrne-Hoffman, W. Deng, O. McGrath…·D. J. Klinke
This study shows IL-12 enhances B16F0 melanoma cell survival through non-canonical PI3K-AKT signaling, distinct from its canonical role in immune cells.
DOI 10.1186/s12964-020-00547-4