Optical Genome Mapping for detecting Homologous Recombination Deficiency (HRD) in human breast and ovarian cancers
S. Vanhuele, Y. Kirova, A.-S. Hamy-Petit, A. Rapinat, D. Gentien, C. Callens, M.-C. Villy, F. Reyal, A. Vincent-Salomon, A. Eeckhoutte, M. Rodrigues, M.-H. Stern, T. Popova
This study uses Optical Genome Mapping to detect HRD in breast and ovarian cancers by analyzing structural variants, finding isolated translocations as a reliable biomarker.
bioRxiv · Dec 23, 2022 · PreprintCancer Biology