Author

A. Rapinat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

D. Gentien· 2 shared E. Chapeaublanc· 2 shared F. Dufour· 2 shared F. Radvanyi· 2 shared I. Bernard-Pierrot· 2 shared J. Fontugne· 2 shared T. Lebret· 2 shared X.-Y. Meng· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

D. Gentien

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Author profile →

3 papers

Recent·Most cited

Optical Genome Mapping for detecting Homologous Recombination Deficiency (HRD) in human breast and ovarian cancers

S. Vanhuele, Y. Kirova, A.-S. Hamy-Petit, A. Rapinat, D. Gentien, C. Callens, M.-C. Villy, F. Reyal, A. Vincent-Salomon, A. Eeckhoutte, M. Rodrigues, M.-H. Stern, T. Popova

This study uses Optical Genome Mapping to detect HRD in breast and ovarian cancers by analyzing structural variants, finding isolated translocations as a reliable biomarker.

bioRxiv · Dec 23, 2022 · PreprintCancer Biology

Epigenomic mapping identifies a super-enhancer repertoire that regulates cell identity in bladder cancers through distinct transcription factor networks

H. Neyret-Kahn, J. Fontugne, X.-Y. Meng, C. S. Groeneveld, L. Cabel, T. Ye, E. Guyon, C. Krucker, F. Dufour, E. Chapeaublanc, A. Rapinat, D. C. B. Jeffery, Y. Neuzillet, T. Lebret, D. Gentien, , F. Radvanyi

The paper identifies super-enhancer networks regulating bladder cancer subtypes through transcription factors, showing their role in cell identity and inflammatory response suppression.

bioRxiv · Jan 11, 2022Cancer Biology

FGFR3 activating mutations induce luminal-like papillary bladder tumor formation and favor a male gender bias.

M. Shi, A. Moreno-Vega, J. Fontugne, X.-Y. Meng, F. Dufour, A. Kamoun, S. V. Lindskrog, A. Rapinat, C. Dunois-Larde, M.-L. Lapage, E. Chapeaublanc, O. Levrel, T. Lebret, A. Almeida, A. De Reynies, , I. BERNARD-PIERROT

This study shows FGFR3-S249C mutations drive luminal-like papillary bladder tumors in mice and correlate with male gender bias and AR activity in human tumors.

bioRxiv · Sep 2, 2021 · PreprintCancer Biology