Author

C. Chiale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. Chattopadhyay Pal· 1 shared A. L. Codrington· 1 shared B. Almassian· 1 shared B. R. Madina· 1 shared C. Metallo· 1 shared D. A. Scott· 1 shared E. Akbulut· 1 shared E. I. Zuniga· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Chattopadhyay Pal

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2 papers

Recent·Most cited

Metabolic Deficiencies Underlie Plasmacytoid Dendritic Cell Exhaustion After Viral Infection

T. T. Greene, Y. Jo, M. Macal, Z. Fang, F. S. Khatri, A. L. Codrington, K. R. Kazane, C. Chiale, E. Akbulut, S. Swaminathan, Y. Fujita, P. Fitzgerald-Bocarsly, T. Cordes, C. Metallo, D. A. Scott, E. I. Zuniga

This study identifies LDHB as a key regulator of pDC IFN-I production and metabolic capacity during viral infection, linking metabolic deficiencies to pDC exhaustion and its dual role in immunity and pathology.

bioRxiv · Feb 28, 2024 · PreprintImmunology

Virus-like vesicles expressing multiple antigens for immunotherapy of chronic hepatitis B

T. O. Yarovinsky, S. W. Mason, M. Menon, M. M. Krady, M. Haslip, B. R. Madina, X. Ma, S. Moshkani, C. Chiale, A. Chattopadhyay Pal, B. Almassian, J. K. Rose, M. D. Robek, V. Nakaar

This paper develops virus-like vesicles (VLV) expressing multiple HBV antigens for immunotherapy of chronic hepatitis B, showing 40% efficacy in a mouse model.

bioRxiv · Feb 19, 2019Immunology