Y. Fujita

This study develops a multiscale mathematical model to predict intrahepatic cccDNA dynamics using serum viral markers, offering a non-invasive method for HBV infection analysis.

This study develops a noninvasive method using viral markers to predict cccDNA levels in HBV patients, validated against liver biopsy data.

The paper identifies direct RNA-RNA interactions between HA and PB2 vRNAs in influenza A virus that are critical for selective genome packaging and viral replication.

This study identifies remdesivir-resistant SARS-CoV-2 mutations using viral reconstruction, mathematical modeling, and molecular dynamics simulations, showing mutations reduce antiviral activity without increasing viral production.

This study identifies the dgc2 gene in Leptolyngbya boryana, showing that its inactivation suppresses motility and enhances biofilm formation, revealing a novel role for c-di-GMP in colony pattern formation.

The paper investigates state transition in Chlamydomonas, finding reduced ST activity near the pyrenoid and structural changes independent of LHCII phosphorylation.

The paper shows that tumor-cell invasion in Drosophila wing imaginal epithelia starts at specific invasion hotspots where JNK signaling and MMP1 activity drive basal extrusion and basement membrane destruction.

The paper shows that phosphate starvation response precedes abscisic acid response in plants under mild drought, using field and controlled experiments.

This study identifies the nucleolus as the site of vRNP formation and vRNA replication in influenza virus-infected cells.

This study shows RNF5 promotes AML growth by regulating RBBP4 and epigenetic pathways, and its inhibition enhances sensitivity to HDAC inhibitors, suggesting it as a therapeutic target and biomarker.

This study identifies novel Streptomyces strains and phages with potential for antibiotic discovery and genetic manipulation.

The paper shows that vSrc-transformed cells in zebrafish embryos extrude from epithelia during mitosis by misorienting cytokinetic rings and disrupting apicobasal polarity.