Profiling multi-body interactions of BCL2 with single-molecule co-immunoprecipitation reveals the molecular mechanism of ABT-199 resistance
The paper uses single-molecule co-immunoprecipitation to profile BCL2 interactions with BH3-only proteins, revealing how mutations affect ABT-199 resistance through quantitative PPI data.
bioRxiv · Feb 4, 2024 · PreprintBiochemistry