Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring.
J. D. Lee, W. Won, K. Kimball, Y. Wang, F. Yeboah, K. Evitts, C. Neiswanger, S. Schattauer, M. Rappleye, S. B. Bremner, C. Chun, N. Smith, D. L. Mack, J. E. Young, C. J. Lee, , A. Berndt
This paper develops a fast, sensitive genetically encoded H2O2 sensor (oROS-G) and demonstrates its use in monitoring H2O2 dynamics in various cell types and models.
bioRxiv · Jan 31, 2024 · PreprintBioengineering