Author

C. Cochain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Zernecke· 4 shared A.-E. Saliba· 3 shared G. Rizzo· 3 shared D. J. Schulz· 2 shared E. Vafadarnejad· 2 shared J.-S. Silvestre· 2 shared M. Roesch· 2 shared P. Arampatzi· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersImmunology

A. Zernecke

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TREM2 limits necrotic core formation during atherogenesis by controlling macrophage survival and efferocytosis

M. Piollet, F. Porsch, G. Rizzo, F. Kapser, D. J. Schulz, M. G. Kiss, K. Schlepckow, E. Morenas-Rodriguez, M. O. Sen, J. Gropper, M. Roesch, L. Goederle, A. Hladik, S. Knapp, M. Colonna, , C. Cochain

This study shows TREM2 deficiency increases necrotic core formation in atherosclerosis by impairing macrophage efferocytosis and survival.

bioRxiv · May 15, 2023 · PreprintImmunology

Integrated scRNA-seq analysis identifies conserved transcriptomic features of mononuclear phagocytes in mouse and human atherosclerosis

A. Zernecke, F. Erhard, T. Weinberger, C. Schulz, K. Ley, A.-E. Saliba, C. Cochain

This study integrates scRNA-seq data from mouse and human atherosclerosis to identify conserved transcriptomic features of mononuclear phagocytes across species.

bioRxiv · Dec 9, 2020Immunology

Time-resolved single-cell transcriptomics uncovers dynamics of cardiac neutrophil diversity in murine myocardial infarction

E. Vafadarnejad, G. Rizzo, L. Krampert, P. Arampatzi, V. A. Nugroho, D. J. Schulz, M. Roesch, P. Alayrac, J. Vilar, J.-S. Silvestre, A. Zernecke, A.-E. Saliba, C. Cochain

This study uses time-resolved single-cell transcriptomics to analyze cardiac neutrophil diversity in murine myocardial infarction, identifying distinct subsets and their temporal dynamics.

Circulation Research · Oct 9, 2020Peer-reviewedImmunology

Single-cell transcriptomic profiling maps monocyte/macrophage transitions after myocardial infarction in mice

G. Rizzo, E. Vafadarnejad, P. Arampatzi, J.-S. Silvestre, A. Zernecke, A.-E. Saliba, C. Cochain

This study maps monocyte/macrophage transitions after myocardial infarction in mice using single-cell transcriptomics, identifying key transcriptional states and regulators.

bioRxiv · Apr 14, 2020Immunology