Cancer BiologybioRxivPreprint
PARG inhibition induces replication catastrophe in ovarian cancer cells with down-regulated DNA replication genes
C. Coulson-Gilmer, R. Morgan, L. Nelson…·S. Taylor
This study shows that PARG inhibition causes replication catastrophe in some ovarian cancer cells with down-regulated DNA replication genes, suggesting a potential biomarker for PARG inhibitor response.
DOI 10.1101/2020.07.13.199968