Author

C. Danchik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:mouse· 2 Research Focus:batch correction / integration· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. Bader· 2 shared P. C. Karakousis· 2 shared W. M. Matern· 2 shared A. Sandhu· 1 shared A. Simeonov· 1 shared A. Srivastava· 1 shared C. Klumpp-Thomas· 1 shared C. Schill· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

J. Bader

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Functional whole genome screen of nutrient-starved Mycobacterium tuberculosis identifies genes involved in antibiotic tolerance

W. M. Matern, H. T. Harris, C. Danchik, M. McDonald, G. Patel, A. Srivastava, T. R. Ioerger, J. Bader, P. C. Karakousis

This study identifies Mtb genes involved in antibiotic tolerance under nutrient-starved conditions through a functional genome screen, revealing potential therapeutic targets.

bioRxiv · Apr 12, 2023 · PreprintMicrobiology

An intranasal stringent response vaccine targeting dendritic cells as a novel adjunctive therapy against tuberculosis

S. Karanika, J. Gordy, P. Neupane, T. KARANTANOS, J. Castillo, D. Quijada, K. Comstock, A. Sandhu, Y. Hui, S. Ayeh, R. Tasneen, S. Krug, C. Danchik, T. Wang, C. Schill, , P. Karakousis

This paper develops a DNA vaccine targeting dendritic cells that enhances isoniazid efficacy against tuberculosis by inducing strong immune responses and reducing Mtb burden.

bioRxiv · Apr 19, 2022Immunology

Genetic determinants of intrinsic antibiotic tolerance in Mycobacterium avium

W. M. Matern, H. Parker, C. Danchik, L. Hoover, J. Bader, P. C. Karakousis

This study identifies antibiotic tolerance genes in Mycobacterium avium through a genome-wide transposon screen, revealing potential targets for improving treatment of MAC infections.

bioRxiv · Feb 23, 2021Microbiology

Keeping it clean: the cell culture quality control experience at the National Center for Advancing Translational Sciences

J. S. Roth, T. D. Lee, D. M. Cheff, M. L. Gosztyla, R. Asawa, C. Danchik, S. Michael, A. Simeonov, C. Klumpp-Thomas, K. Wilson, M. D. Hall

The paper describes NCATS's implementation of mycoplasma and STR testing to improve cell line quality, reducing contamination and misidentification in translational research.

bioRxiv · Oct 9, 2019Cell Biology