Author

C. E. Castro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Kucinic· 2 shared C. M. Huang· 2 shared A. Chowdhury· 1 shared A. E. Dejanov· 1 shared A. Marson· 1 shared B. R. Shy· 1 shared C. R. S. Espinoza· 1 shared D. M. Lopez· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersScientific Communication & Education

A. Kucinic

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Steric Communication between Dynamic Components on DNA nanodevices

Y. Wang, S. Sensale, M. Pedrozo, C. M. Huang, M. G. Poirier, G. Arya, C. E. Castro

This paper introduces a DNA origami-based method for steric communication between dynamic components, demonstrating signal transmission through thermal fluctuations and conformational regulation.

bioRxiv · Dec 15, 2022Bioengineering

Translating DNA origami Nanotechnology to Middle School, High School, and Undergraduate Laboratories

P. E. Beshay, A. Kucinic, N. Wile, P. Halley, L. Des Rosiers, A. Chowdhury, J. L. Hall, C. E. Castro, M. W. Hudoba

This paper develops a streamlined DNA origami protocol for educational labs, enabling students to fabricate and analyze nanostructures in a 2-hour course with low-cost materials.

bioRxiv · Sep 15, 2022Scientific Communication & Education

CRISPR-Cas9 mediated nuclear transport and genomic integration of nanostructured genes in human primary cells

E. Lin Shiao, W. G. Pfeifer, B. R. Shy, M. S. Doost, E. Chen, V. S. Vykunta, J. R. Hamilton, E. C. Stahl, D. M. Lopez, C. R. S. Espinoza, A. E. Dejanov, R. J. Lew, M. G. Poirer, A. Marson, C. E. Castro, J. A. Doudna

This study delivers DNA nanostructures into human primary cells using CRISPR-Cas9, achieving efficient genomic integration with lower toxicity than dsDNA.

bioRxiv · Nov 8, 2021 · PreprintBioengineering

Integrating computer-aided engineering and computer-aided design for DNA assemblies

C. M. Huang, A. Kucinic, J. A. Johnson, H. Su, C. E. Castro

The paper presents a design pipeline for DNA assemblies integrating CAD and CAE to enhance structural complexity and mechanical design.

bioRxiv · May 28, 2020Bioengineering