Cancer BiologybioRxiv
Perivascular macrophages collaborate to facilitate chemotherapy resistance in cancer
J. E. Anstee, J. W. Opzoomer, I. Dean…·J. N. Arnold
This study identifies Lyve-1+ perivascular macrophages that form nests and contribute to chemotherapy resistance by excluding CD8+ T-cells and relying on IL-6 and CCR5/CCL3/4 signaling.
DOI 10.1016/j.devcel.2023.06.006