ImmunologybioRxivPreprint
Tailoring Tfh Profiles Enhances Antibody Persistence to a Clade C HIV-1 Vaccine in Rhesus Macaques
A. Verma, C. E. Hawes, S. R. Elizaldi…·S. S. Iyer
This study shows that inducing GC Tfh1 cells with MPLA+QS-21 adjuvant leads to higher and longer-lasting HIV-1 Env antibodies in rhesus macaques compared to CAF01.
DOI 10.1101/2023.07.18.549515