BiochemistrybioRxivPreprint
Non-Canonical Binding of a Small Molecule to Sortilin Alters Cellular Trafficking of ApoB and PCSK9 in Liver Derived Cells
R. P. Sparks, A. S. Arango, Z. L. Aboff…·R. A. Fratti
The paper investigates how a small molecule alters Sortilin's function, affecting ApoB and PCSK9 trafficking in liver cells and revealing a conserved mechanism in yeast.