Author

C. Farquharson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1

Frequent Co-Authors

C. Huesa· 2 shared K. A. Staines· 2 shared K. J. Suchacki· 2 shared A. A. S. Tavares· 1 shared A. R. Guntur· 1 shared B. J. Thomas· 1 shared C. J. Alcaide-Corral· 1 shared C. J. Rosen· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPathology

C. Huesa

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability

H. J. Samvelyan, C. Huesa, L. Cui Lin, C. Farquharson, K. A. Staines

This study examines whether accelerated growth due to SOCS2 deletion affects osteoarthritis vulnerability in mice, finding no effect on disease susceptibility despite changes in growth plate fusion.

bioRxiv · May 13, 2021Pathology

Proton pump inhibitors inhibit PHOSPHO1 activity and matrix mineralisation in vitro

K. A. Staines, K. Myers, K. Little, S. H. Ralston, C. Farquharson

This study shows that proton pump inhibitors inhibit PHOSPHO1 activity and bone matrix mineralisation in vitro, suggesting a mechanism for their association with fracture risk.

bioRxiv · Apr 29, 2021Cell Biology

A systems-level analysis of dynamic total-body PET data reveals complex skeletal energy metabolism networks in vivo

K. J. Suchacki, C. J. Alcaide-Corral, S. Nimale, M. G. Macaskill, R. H. Stimson, C. Farquharson, T. C. Freeman, A. A. S. Tavares

The paper uses total-body PET scans to analyze dynamic skeletal energy metabolism networks in mice, revealing unique glucose metabolism patterns across bones and their complex interactions.

bioRxiv · Feb 16, 2021Physiology

PHOSPHO1, a novel skeletal regulator of insulin resistance and obesity

K. J. Suchacki, N. M. Morton, C. Vary, C. Huesa, M. C. Yadav, B. J. Thomas, S. Rajoanah, L. Bunger, D. Ball, M. Barrios-Llerena, A. R. Guntur, Z. Khavandgar, W. P. Cawthorn, M. Ferron, G. Karsenty, , C. Farquharson

This study shows that PHOSPHO1 deficiency improves glucose homeostasis and protects against obesity and diabetes without altering osteocalcin levels.

bioRxiv · May 4, 2020 · PreprintPhysiology