In Vivo Tissue Distribution of Microplastics and Systemic Metabolomic Alterations After Gastrointestinal Exposure
M. M. Garcia, A. S. Romero, S. D. Merkley, J. L. Meyer-Hagen, C. Forbes, E. El Hayek, D. P. Sciezka, R. Templeton, J. Gonzalez-Estrella, Y. Jin, H. Gu, A. Benavidez, R. P. Hunter, S. Lucas, G. Herbert, , E. F. Castillo
This study shows that ingested microplastics can cross the gut barrier, enter systemic circulation, accumulate in tissues, and alter metabolomic profiles in mice.
bioRxiv · Jun 2, 2023 · PreprintPharmacology & Toxicology