Author

C. Forsberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Organism:mouse· 6 Assay:bulk RNA-seq· 4 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Worthington· 3 shared A. Beaudin· 2 shared D. Poscablo· 2 shared R. Reggiardo· 2 shared S. Smith-Berdan· 2 shared S. W. Boyer· 2 shared T. Cool· 2 shared A. Terskikh· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

A. Worthington

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

An age-specific platelet differentiation path from hematopoietic stem cells contributes to exacerbated thrombosis

D. Poscablo, A. Worthington, S. Smith-Berdan, B. Manso, R. Adili, T. Cool, R. Reggiardo, S. Dahmen, A. Beaudin, S. W. Boyer, M. Holinstat, C. Forsberg

This paper identifies an age-specific platelet differentiation pathway from hematopoietic stem cells that contributes to thrombosis and platelet hyperreactivity in aging.

bioRxiv · Feb 23, 2024Cell Biology

Megakaryocyte Progenitor Cell Function is Enhanced Upon Aging Despite the Functional Decline of Aged Hematopoietic Stem Cells

D. Poscablo, A. Worthington, S. Smith-Berdan, C. Forsberg

This study shows that aging impairs hematopoietic stem cells but enhances megakaryocyte progenitor cell function and expansion.

Stem Cell Reports · Jun 1, 2021Peer-reviewedCell Biology

A Quantitative Hematopoietic Stem Cell Reconstitution Protocol:Accounting for Recipient Variability, Tissue Distribution and Cell Half-Lives

S. Rajendiran, S. W. Boyer, C. Forsberg

This paper introduces a protocol to quantitatively assess hematopoietic stem cell reconstitution in mice by accounting for recipient variability, tissue distribution, and cell half-lives.

bioRxiv · Dec 3, 2020Cell Biology

Chromatin Accessibility Maps Provide Evidence of Multilineage Gene Priming in Hematopoietic Stem Cells

E. Martin, J. Krietsch, R. Reggiardo, R. Sousae, D. Kim, C. Forsberg

The paper uses ATAC-seq to compare chromatin accessibility in hematopoietic stem cells with unipotent cell types, finding evidence of lineage-specific cis element priming and differences in accessibility patterns.

bioRxiv · Nov 24, 2020Cell Biology

Ubiquitous overexpression of CXCL12 confers radiation protection and enhances mobilization of hematopoietic stem and progenitor cells

C. Forsberg

This study shows that ubiquitous CXCL12 overexpression in mice increases hematopoietic progenitors, reduces transplant reconstitution, enhances stem cell mobilization, and provides radioprotection.

bioRxiv · Jan 8, 2020Cell Biology

Improving drug discovery using image-based multiparametric analysis of epigenetic landscape.

C. Farhy, S. Hariharan, J. Ylanko, L. Orozco, F.-Y. Zeng, I. Pass, F. Ugarte, C. Forsberg, C.-T. Huang, D. Andrews, A. Terskikh

This paper introduces MIEL, an image-based method for epigenetic drug screening, showing it can detect active compounds, classify functions, and predict novel drug effects with higher resolution than traditional methods.

bioRxiv · May 15, 2019Cell Biology

The lymphoid-associated interleukin 7 receptor (IL-7R) regulates tissue resident macrophage development

G. Leung, T. Cool, C. Valencia, A. Worthington, A. Beaudin, C. Forsberg

This study shows that IL-7R regulates fetal-derived tissue-resident macrophage development through dynamic expression and progenitor-progeny relationships.

bioRxiv · Jan 30, 2019Immunology