C. Guenther

Stiffness regulates dendritic cell and macrophage subtype development and increased stiffness induces a tumor-associated macrophage phenotype in cancer co-cultures

This study shows that tissue stiffness influences dendritic cell and macrophage subtype development, with increased stiffness promoting a tumor-associated macrophage phenotype in cancer co-cultures.

Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

This study identifies human Dectin-1 as a ligand for CLEC-2, showing its O-glycosylation enables it to function as a physiological ligand for immune regulation.

Validation of an RNase H2 activity assay suitable for clinical screening

The paper validates a FRET-based assay for measuring RNase H2 activity in clinical samples, showing it can detect reduced activity in patient lymphocytes.