Author

C. Guha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Bergman· 1 shared B. I. Bell· 1 shared C. J. Shawber· 1 shared C. Velten· 1 shared C. Xu· 1 shared D. K. Borger· 1 shared E. T. Malagola· 1 shared J. English· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. Bergman

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3 papers

Recent·Most cited

Haematopoietic stem cell numbers are not solely determined by niche availability

S. Takeishi, T. Marchand, W. R. Koba, D. K. Borger, C. Xu, C. Guha, A. Bergman, P. S. Frenette, K. Gritsman, U. Steidl

This study challenges the idea that HSC numbers are solely determined by niche availability, showing systemic and local constraints on HSC numbers regardless of niche changes.

bioRxiv · Oct 28, 2023 · PreprintCell Biology

Immature myeloid cells are indispensable for intestinal regeneration post irradiation injury

Z. Jiang, Q. T. Waterbury, N. Fu, W. Kim, E. T. Malagola, C. Guha, C. J. Shawber, K. S. Yan, T. C. Wang

This study shows that immature myeloid cells (IMCs) are essential for intestinal regeneration after irradiation injury, driven by microbial signals and promoting epithelial repair through PGE2 production.

bioRxiv · Feb 28, 2023 · PreprintPhysiology

Increased Relative Biological Effectiveness of Orthovoltage X-rays Compared to γ-rays in Preclinical Irradiation

B. I. Bell, J. Vercellino, N. P. Brodin, C. Velten, L. S. Y. Nanduri, K. E. Tanaka, Y. Fang, Y. Wang, R. Macedo, J. English, M. M. Schumacher, P. K. Duddempudi, P. Asp, W. Koba, S. Shajahan, , C. Guha

This study compares the biological effects of orthovoltage X-rays and 137Cs γ-rays in mouse models, finding that lower-energy X-rays cause more severe hematopoietic and intestinal injury at equivalent physical doses.

bioRxiv · Feb 18, 2022Pathology