Author

C. Huerta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Ecology· 2 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:Drosophila· 2 Assay:bulk RNA-seq· 1 Research Focus:ecology & biodiversity· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Baird· 2 shared E. S. Davenport· 2 shared F. E. Corcoran· 2 shared K. M. McIntire· 2 shared M. A. Duffy· 2 shared M. K. Dziuba· 2 shared R. Jaye· 2 shared A. Salamov· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersEcology

E. Baird

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Author profile →

4 papers

Recent·Most cited

Microsporidian coinfection reduces fitness of a fungal pathogen due to rapid host mortality

M. K. Dziuba, K. M. McIntire, E. S. Davenport, E. Baird, C. Huerta, R. Jaye, F. E. Corcoran, P. McCreadie, T. Nelson, M. A. Duffy

The paper shows that coinfection with two pathogens reduces host survival but limits the spread of the more virulent pathogen, suggesting potential population-level benefits.

bioRxiv · Feb 8, 2024Ecology

Phylogeny, morphology, virulence, ecology, and host range of Ordospora pajunii (Ordosporidae), a microsporidian symbiont of Daphnia spp.

M. K. Dziuba, K. M. McIntire, K. Seto, E. S. Davenport, M. A. Rogalski, C. D. Gowler, E. Baird, M. Vaandrager, C. Huerta, R. Jaye, F. E. Corcoran, A. Withrow, S. Ahrendt, A. Salamov, M. Nolan, , M. A. Duffy

This paper investigates the impact of Ordospora pajunii on Daphnia hosts, finding low virulence and context-dependent effects, and identifies it as a valuable model for studying mutualism-parasitism shifts.

bioRxiv · Apr 21, 2023 · PreprintEcology

NK cells promote cancer immunoediting through tumor-intrinsic loss of interferon-stimulated gene expression

Y. Y. Wong, L. Riggan, C. Huerta, M. Moldenhauer, E. Perez Reyes, T. E. O'Sullivan

This study shows that NK cell-edited tumors lose IFN-γ-inducible gene expression, and high expression of three genes correlates with better patient survival in breast, melanoma, and sarcoma.

bioRxiv · Nov 23, 2020 · PreprintImmunology

Structural basis of recruitment of RBM39 to DCAF15 by a sulfonamide molecular glue E7820

X. Du, O. A. Volkov, R. Czerwinski, H. Tan, C. Huerta, E. Morton, J. Rizzi, P. Wehn, R. Xu, D. Nijhawan, E. Wallace

The paper investigates how E7820 recruits RBM39 to the DCAF15 E3 ligase complex through structural and kinetic analysis, revealing its mechanism as a molecular glue.

bioRxiv · Sep 5, 2019Biophysics