Cancer BiologybioRxivPreprint
Cell-extrinsic effects in T cell acute lymphoblastic pre-leukemia stem cells mediated by EphA3
A. C. Pliego Zamora, H. Ranasinghe, J. E. Lisle…·C. I. Slape
The paper investigates the role of EphA3 in T cell acute lymphoblastic pre-leukemia stem cells, showing it enables the halt in differentiation of neighboring WT cells, allowing pre-leukemic cells to persist in the thymus.
DOI 10.1101/2020.09.14.297127