Author

C. Iorio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

L. Wells· 2 shared A. C.-H. Ng· 1 shared B. McDonnell· 1 shared B. Zhang· 1 shared C. Reeks· 1 shared E. Moon· 1 shared F. Vyas· 1 shared J. L. Rourke· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

L. Wells

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice

L. M. Podmore, Y. Poloz, C. Iorio, S. Mouaaz, K. Nixon, P. Smirnov, B. McDonnell, S. Lam, B. Zhang, P. Tharmapalan, S. Sarkar, F. Vyas, M. Ennis, R. Dowling, V. Stambolic

This study shows that insulin receptor loss delays mammary tumor onset and burden in mouse models, without affecting progression or metastasis.

bioRxiv · May 6, 2022Cancer Biology

Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β CellProliferation

C. Iorio, J. L. Rourke, L. Wells, J.-I. Sakamaki, E. Moon, Q. Hu, T. Kin, R. Screaton

This study identifies the GPR3-SIK2 pathway as a regulator of human β cell proliferation, showing that GPR3 silencing activates SIK2 to drive cell cycle entry and increase β cell mass.

bioRxiv · May 31, 2021Cell Biology

ROMO1 and Mitochondrial Complex II/SDH are Required for Spare Respiratory Capacity and Glucose Homeostasis in Mice

L. Wells, Q. Yang, C. Iorio, M. Peragerasingam, Z. Campbell, A. C.-H. Ng, C. Reeks, S.-P. Yee, R. A. Screaton

This study shows that ROMO1 is essential for mouse development and maintains spare respiratory capacity and glucose homeostasis in pancreatic beta cells.

bioRxiv · Apr 28, 2021Cell Biology