Author

C. J. Dwyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. S. Smith· 3 shared C. M. Paulos· 3 shared G. O. Rangel Rivera· 3 shared M. M. Wyatt· 3 shared A. M. Rivera-Reyes· 2 shared D. M. Neskey· 2 shared H. M. Knochelmann· 2 shared J. E. Thaxton· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersImmunology

A. S. Smith

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 8, 2023

The degree of T cell stemness differentially impacts the potency of adoptive cancer immunotherapy in a Lef-1 and Tcf-1 dependent manner.

G. O. Rangel Rivera, C. J. Dwyer, H. Knochelmann…·C. M. Paulos

This study shows that varying levels of PI3Kδ pathway inhibition affect T cell stemness, with higher stemness improving cancer immunotherapy outcomes in multiple tumor models.

DOI 10.1101/2023.03.08.531589

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivMar 16, 2021

B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity

A. S. Smith, H. M. Knochelmann, M. M. Wyatt…·C. M. Paulos

This study shows that CpG-mediated expansion with B cells enhances CD8+ T cell tumor immunity by inducing a unique proteomic signature and specific surface markers.

DOI 10.1136/jitc-2021-003078

mouseproteomics

𝕏 PostBluesky

ImmunologybioRxivFeb 4, 2021

Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

H. M. Knochelmann, A. M. Rivera-Reyes, M. M. Wyatt…·C. M. Paulos

The paper expands murine tumor-infiltrating lymphocytes ex vivo in IL-2 and compares their phenotypes to human TILs from oral cavity cancer patients.

DOI 10.1080/2162402x.2021.1959101

mouseproteomics

𝕏 PostBluesky