Cell BiologybioRxivPreprint
Replicative aging impedes stress-induced assembly of a key human protein disaggregase
Y. Mathangasinghe, N. Alberts, C. J. Rosado…·N. B. Nillegoda
This study identifies a stress-induced trimeric protein disaggregase in human cells that collapses during replicative aging, contributing to pathophysiological consequences.
DOI 10.1101/2022.06.25.497591