Author

C. Kikawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:virus· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. H. Cartwright-Acar· 2 shared J. D. Bloom· 2 shared L. Goo· 2 shared L. M. Levoir· 2 shared M. Contreras· 2 shared M. J. Evans· 2 shared A. M. Sanz· 1 shared A. S. de Godoy· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

C. H. Cartwright-Acar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors

X. Ni, R. B. Richardson, A. S. de Godoy, M. P. Ferla, C. Kikawa, J. Scheen, W. W. Hannon, E. Capkin, N. Lahav, B. H. Balcomb, P. G. Marples, M. Fairhead, S. Wang, E. Williams, C. W. E. Tomlinson, , F. von Delft

The paper identifies fragment binders and mutationally intolerant sites in Zika virus NS2B-NS3 protease to develop resistance-resilient antiviral inhibitors.

bioRxiv · Apr 29, 2024 · PreprintBiochemistry

Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses

J. Lubow, L. M. Levoir, D. K. Ralph, L. Belmont, M. Contreras, C. H. Cartwright-Acar, C. Kikawa, S. Kannan, E. Davidson, B. J. Doranz, V. Duran, D. E. Sanchez, A. M. Sanz, F. Rosso, S. Einav, , L. Goo

The paper uses single-cell transcriptomics to identify new broadly neutralizing antibodies against flaviviruses, including an IgA1 isotype with unique neutralizing properties.

PLOS Pathogens · Oct 9, 2023Peer-reviewedMicrobiology

The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies

L. Goo, C. Kikawa, C. H. Cartwright-Acar, J. B. Stuart, M. Contreras, L. M. Levoir, M. J. Evans, J. D. Bloom

This study identifies how single mutations in Zika virus envelope protein affect neutralization by broadly and narrowly specific antibodies, finding that broad antibodies are harder to escape.

bioRxiv · Sep 13, 2023Microbiology