Author

C. Knobbe-Thomsen

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:mouse· 1

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A. Calvet· 1 shared A. D. Garg· 1 shared A. Datsi· 1 shared D. Borras· 1 shared G. Kroemer· 1 shared I. Vanmeerbeek· 1 shared J. Borst· 1 shared J. Govaerts· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Calvet

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1 paper

Recent·Most cited

ImmunologyCell Reports MedicinePeer-reviewedJan 1, 2024

A lymph node-to-tumour PD-L1+macrophage circuit antagonizes dendritic cell immunotherapy

J. Sprooten, I. Vanmeerbeek, A. Datsi…·A. D. Garg

This paper shows that DC vaccines can activate PD-L1+ macrophages in lymph nodes and tumors, creating an immunosuppressive circuit that limits their effectiveness, but this can be overcome by combining with PD-L1 blockade.

DOI 10.1016/j.xcrm.2023.101377

mousebulk RNA-seq

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