Author

C. Lancey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

T. J. Ragan· 2 shared A. De Biasio· 1 shared A. M. Frank· 1 shared A. Shirbini· 1 shared C. Savva· 1 shared C. Ying· 1 shared E. Hesketh· 1 shared F. J. Blanco· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

T. J. Ragan

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2 papers

Recent·Most cited

Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP and its antibody response characterisation

S. Batra, F. Olmo, T. J. Ragan, A. M. Frank, M. Kaplan, C. Lancey, M. Assadipapari, C. Ying, W. B. Struwe, E. Hesketh, J. M. Kelly, L. Barfod, I. Campeotto

This study determines the 3D structures of TcPOP in open and closed conformations using cryo-EM and evaluates its immunogenicity through antibody responses in mice.

bioRxiv · Mar 26, 2024 · PreprintBiophysics

Structure of the processive human Pol δ holoenzyme

C. Lancey, M. Tehseen, V.-S. Raducanu, F. Rashid, N. Merino, T. J. Ragan, C. Savva, M. S. Zaher, A. Shirbini, F. J. Blanco, S. M. Hamdan, A. De Biasio

This study presents the high-resolution cryo-EM structure of the human Pol δ-DNA-PCNA complex with and without FEN1, revealing its structural basis for DNA replication.

bioRxiv · Dec 11, 2019Biochemistry