Author

S. Batra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Kumar· 1 shared A. Lemoff· 1 shared A. M. Frank· 1 shared A. McCarthy· 1 shared A. S. Krall· 1 shared A. Viale· 1 shared B. Prakash· 1 shared B. S. Nelson· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Kumar

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP and its antibody response characterisation

S. Batra, F. Olmo, T. J. Ragan, A. M. Frank, M. Kaplan, C. Lancey, M. Assadipapari, C. Ying, W. B. Struwe, E. Hesketh, J. M. Kelly, L. Barfod, I. Campeotto

This study determines the 3D structures of TcPOP in open and closed conformations using cryo-EM and evaluates its immunogenicity through antibody responses in mice.

bioRxiv · Mar 26, 2024 · PreprintBiophysics

VCP increases or decreases tau seeding using specific cofactors

S. Batra, J. I. Vaquer-Alicea, V. A. Manon, O. M. Kashmer, A. Lemoff, N. J. Cairns, C. L. I. White, M. I. Diamond

This study investigates how VCP and its cofactors influence tau seeding efficiency in cellular models, finding that VCP modulates this process through distinct cofactors.

bioRxiv · Aug 30, 2023Cell Biology

The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replisome collisions

C. Kumar, S. Batra, J. Griffith, D. Remus

This study investigates how RNA:DNA hybrid structures and G-quadruplexes influence R-loop-replisome collisions, showing structural differences determine replication outcomes.

bioRxiv · Jul 16, 2021Biochemistry

Alternative catalytic mechanisms driven by structural plasticity is an emerging theme in HAS-GTPases, Era and FeoB

S. Batra, A. Kumar, B. Prakash

This study investigates alternative catalytic mechanisms in HAS-GTPases, showing that structural plasticity allows GTP hydrolysis even when key residues are mutated.

bioRxiv · Aug 16, 2020 · PreprintBiochemistry

Clonal Heterogeneity Supports Mitochondrial Metabolism in Pancreatic Cancer

C. J. Halbrook, G. Thurston, A. McCarthy, B. S. Nelson, P. Sajjakulnukit, A. S. Krall, P. J. Mullen, L. Zhang, S. Batra, A. Viale, B. Z. Stanger, H. R. Cristofk, J. Zhang, M. Pasca di Magliano, C. Jorgensen, C. A. Lyssiotis

The paper identifies two metabolic subclasses in pancreatic cancer cells and shows asparagine's role in supporting proliferation under mitochondrial stress, suggesting a new therapeutic strategy.

bioRxiv · May 15, 2020 · PreprintCancer Biology