Cancer BiologybioRxivPreprint
The G protein-coupled receptor TBXA2R activates ERMs to control cell motility and invasion of triple-negative breast cancer cells.
DOI 10.1101/2023.03.28.534587
Author
C. Le Gouill
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2020-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 24 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- Pharmacology & ToxicologybioRxivPreprint
Vasopressin V2 is a promiscuous G protein-coupled receptor that is biased by its peptide ligands
F. M. Heydenreich, B. Plouffe, A. Rizk…·D. Veprintsev
The paper shows that the vasopressin V2 receptor activates multiple G proteins and that its signaling can be biased by ligand structure.
DOI 10.1101/2021.01.28.427950 - Pharmacology & ToxicologybioRxivPreprint
Diverse chemotypes drive biased signaling by cannabinoid receptors
T. Miljus, F. M. Heydenreich, T. Gazzi…·D. B. Veprintsev
This study identifies chemotype-specific biased signaling in cannabinoid receptors by analyzing ligand-induced signaling cascades.
DOI 10.1101/2020.11.09.375162 - Pharmacology & ToxicologybioRxiv
Effector membrane translocation biosensors reveal G protein and β-arrestin coupling profiles of 100 therapeutically relevant GPCRs
C. Avet, A. Mancini, B. Breton…·M. Bouvier
The paper develops EMTA biosensors to profile G protein and β-arrestin coupling of 100 GPCRs, revealing diverse signaling profiles and drug-target interactions.
DOI 10.7554/elife.74101