Author

C. Leslie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Rudensky· 1 shared A. Y. Rudensky· 1 shared B. Akagbosu· 1 shared C. Brown· 1 shared C. C. Brown· 1 shared C. Friedrich· 1 shared D. Deep· 1 shared G. Gasteiger· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Rudensky

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Author profile →

2 papers

Recent·Most cited

Reconciling the spectrum of RORγt+ antigen-presenting cells

T. Park, C. Leslie, A. Rudensky, C. Brown

The paper reanalyzes single-cell RNA-seq data from three studies to reconcile discrepancies in identifying RORγt+ antigen-presenting cells and their role in pTreg induction.

bioRxiv · Nov 1, 2023 · PreprintImmunology

A novel RORγt+ antigen presenting cell type instructs microbiota-dependent regulatory T cell differentiation and tolerance during early life

B. Akagbosu, Z. Tayyebi, G. Shibu, Y. A. Paucar Iza, D. Deep, Y. Franco Parisotto, H. A. Pasolli, V. Thevin, R. Elmentaite, M. Knott, S. Hemmers, L. Jahn, C. Friedrich, J. Verter, Z. Wang, , C. C. Brown

This study identifies a new RORγt+ antigen-presenting cell type, Thetis cells, that drives microbiota-dependent regulatory T cell differentiation and tolerance during early life.

bioRxiv · Feb 26, 2022Immunology