Author

T. Park

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 3 Cancer Biology· 3 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Approach:statistical model· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Assay:metabolomics· 2

Frequent Co-Authors

E. M. Liu· 2 shared E. Reznik· 2 shared J. Lee· 2 shared A. A. Hakimi· 1 shared A. H. Uribe· 1 shared A. L. Shergold· 1 shared A. L. Young· 1 shared A. M. Intlekofer· 1 shared

Activity by Year

2018-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

E. M. Liu

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Reconciling the spectrum of RORγt+ antigen-presenting cells

T. Park, C. Leslie, A. Rudensky, C. Brown

The paper reanalyzes single-cell RNA-seq data from three studies to reconcile discrepancies in identifying RORγt+ antigen-presenting cells and their role in pTreg induction.

bioRxiv · Nov 1, 2023 · PreprintImmunology

An autochthonous model of lung cancer in the Naked Mole-Rat (Heterocephalus glaber)

J. Kissil, A. Shepard, S. Troutman, S. Hoxha, D. Lester, W. Khaled, E. S. J. Smith, T. Park, R. Buffenstein, D. Dongliang, M. S. J. Teng, C. Crish, K. Tsai, E. Flores, A. Ventura

This study develops an endogenous lung cancer model in naked mole-rats, showing tumor initiation more closely resembles human tumors than in mice.

bioRxiv · Aug 28, 2023Cancer Biology

Metabolic influence of core ciliates within the rumen microbiome

T. O. Andersen, I. Altshuler, A. V. P. de Leon, J. Walter, E. McGovern, K. Keogh, C. Martin, L. Bernard, D. P. Morgavi, T. Park, Z. Li, Y. Jiang, J. L. Firkins, Z. Yu, T. R. Hvidsten, , P. B. Pope

The paper investigates the metabolic roles of core ciliates in the rumen microbiome, finding that they contribute significantly to volatile fatty acid production and hydrogen metabolism, particularly in high methane-emitting animals.

The ISME Journal · Jul 1, 2023Peer-reviewedMicrobiology

Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade

M. Mahmood, E. M. Liu, A. L. Shergold, E. Tolla, J. Tait-Mulder, A. H. Uribe, E. Shokry, A. L. Young, S. Lilla, M. Kim, T. Park, J. L. Manchon, C. Rodriguez-Antona, R. C. Walters, R. J. Springett, , P. A. Gammage

This study shows that mitochondrial DNA mutations in complex I genes drive aerobic glycolysis, enhancing immune checkpoint blockade response in tumors.

bioRxiv · Mar 21, 2023 · PreprintCancer Biology

A Multimodal Atlas of Tumor Metabolism Reveals the Architecture of Gene-Metabolite Co-regulation

E. Benedetti, E. M. Liu, C. Tang, F. Kuo, M. Buyukozkan, T. Park, J. Park, F. Correa, A. A. Hakimi, A. M. Intlekofer, J. Krumsiek, E. Reznik

The paper constructs a multimodal tumor metabolism atlas to identify gene-metabolite co-regulation patterns across cancer types.

bioRxiv · Nov 23, 2022 · PreprintCancer Biology

Turbulent adaptive landscape shaped size evolution in modern ocean giants

G. Burin, T. Park, T. D. James, G. Slater, N. Cooper

This study analyzes the adaptive landscape of cetacean body size over 53 million years, showing a relatively flat global landscape with local peaks linked to specific adaptations.

bioRxiv · Sep 7, 2022 · PreprintEvolutionary Biology

Microscope-Cockpit: Python-based bespoke microscopy for bio-medical science

M. A. Phillips, D. M. Susano Pinto, N. Hall, J. Mateos-Langerak, R. M. Parton, D. V. Stoychev, T. Park, T. S. Pinto, J. W. Sedat, M. J. Booth, I. Davis, I. M. Dobbie

The paper introduces Microscope-Cockpit, a Python-based GUI for controlling bespoke microscopes, enabling efficient specimen navigation and hardware integration through open-source tools.

bioRxiv · Jan 18, 2021Biophysics

Lipid membranes from naked mole-rat brain lipids are cholesterol-rich, highly phase-separated, and sensitive to amyloid-induced damage

D. FRANKEL, E. St John Smith, K. Rankin, N. Cenac, M. Davies, J. R. Kumita, M. Vendruscolo, Y. Kulaberoglu, P. Urriola Munoz, J. Bertrand-michel, M. R. Pergande, S. Preet, T. Park, A. Smith, B. Bhushan, S. Cologna

This study examines lipid composition and amyloid beta interactions in naked mole-rat brain membranes, finding they are cholesterol-rich, highly phase-separated, and more susceptible to amyloid-induced damage compared to mouse membranes.

bioRxiv · Jun 5, 2020 · PreprintBiophysics

Developing a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane

H. Woo, S.-J. Park, Y. K. Choi, T. Park, M. Tanveer, Y. Cao, N. R. Kern, J. Lee, M. S. Yeom, T. I. Croll, C. Seok, W. Im

The paper models and simulates a fully-glycosylated SARS-CoV-2 spike protein in a viral membrane using computational methods and provides the structures for research on COVID-19 prevention and treatment.

bioRxiv · May 20, 2020Biophysics

RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction point

J. Lee, D. Kim, J. Jang, T. Park, Y. Lee, X.-Z. Chi, I. Y. Park, J. Hyun, Y. Ito, S.-C. Bae

This study shows RUNX3 regulates chromatin dynamics at the restriction point by opening and closing target loci through recruitment of chromatin modifiers, influencing cell cycle progression and tumor development.

bioRxiv · Sep 7, 2018Cell Biology