MicrobiologybioRxiv
Structural basis of Toxoplasma gondii Perforin-Like Protein 1 membrane interaction and activity during egress
A. J. Guerra, O. Zhang, C. M. E. Bahr…·V. B. Carruthers
This study identifies the structural basis of TgPLP1 membrane interaction and its role in parasite egress by showing a hydrophobic loop insertion into the membrane is essential for cytolytic activity.
DOI 10.1371/journal.ppat.1007476