BiochemistrybioRxiv
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by singleparticle cryo-EM
C. M. Highland, A. Tan, C. L. Ricana…·R. A. Dick
This study uses cryo-EM to determine high-resolution structures of HIV-1 capsid lattices containing hexamers and pentamers, revealing the role of IP6 in pentamer formation and the structure of the lattice bound to the drug GS-6207.