MicrobiologybioRxiv
Macrophages utilize a bet-hedging strategy for antimicrobial activity in phagolysosomal acidification
Q. Dragotakes, K. Stouffer, M. S. Fu…·A. Casadevall
The paper shows macrophages use a bet-hedging strategy by stochastically acidifying phagolysosomes to reduce variation in antimicrobial effectiveness.