Author

C. Metcalfe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Sundararajan· 1 shared C. Kohout· 1 shared C. Woodson· 1 shared D. Casane· 1 shared E. G. Pamer· 1 shared E. Garcia-Machado· 1 shared E. S. Snitkin· 1 shared F. Haro· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. Sundararajan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile

Q. Dong, H. Lin, M.-M. Allen, J. R. Garneau, J. K. Sia, R. C. Smith, F. Haro, T. McMillen, R. L. Pope, C. Metcalfe, V. Burgo, C. Woodson, N. Dylla, C. Kohout, A. Sundararajan, , E. G. Pamer

This study identifies a 69 base-pair deletion in the cdtR gene that attenuates virulence in ST1 C. difficile strains without affecting colonization.

bioRxiv · Jan 12, 2023Microbiology

Genomic evidence that blind cavefishes are not wrecks of ancient life

M. Policarpo, P. Laurenti, E. Garcia-Machado, C. Metcalfe, S. Retaux, D. Casane

The paper estimates the age of blindness in cavefishes by analyzing decay in eye-specific genes, finding that blindness is relatively recent, ranging from the Early Pliocene to Late Pleistocene.

bioRxiv · Jun 2, 2021 · PreprintEvolutionary Biology