E. G. Pamer

This study shows that lantibiotic resistance genes in gut bacteria affect microbiota composition and function, with implications for microbiome health and resistance strategies.

The paper characterizes six gut-derived nisin-like lantibiotics, evaluates their antimicrobial activity against pathogens and commensals, and identifies key residues affecting their activity.

The paper identifies that longer inverted repeats in the flagellar switch region of C. difficile RT027 strains correlate with greater virulence and phenotypic heterogeneity in flagellar gene expression.

This study identifies a 69 base-pair deletion in the cdtR gene that attenuates virulence in ST1 C. difficile strains without affecting colonization.

The paper identifies gut bacteria that use dietary and host-derived metabolites as electron acceptors in anaerobic respiration, revealing new metabolic pathways and reductase evolution.

The paper introduces TaxUMAP, a visualization tool for microbiome data, revealing that Klebsiella species reduce bacteremia risk through competition with other pathogens.

This study examines the relationship between gut microbiota composition and monocyte recovery after hematopoietic stem cell transplantation, finding no significant association in a small cohort.