Chromatin loading of MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entry
Y. Hayashi-Takanaka, Y. Hayashi, Y. Hirano, A. Miyawaki-Kuwakado, Y. Ohkawa, C. Obuse, H. Kimura, T. Haraguchi, Y. Hiraoka
This study investigates MCM hexamer states during the cell cycle in human cells and links their formation to histone H4K20 methylation levels, showing that di/trimethyl-H4K20 correlates with double MCM hexamer formation.
bioRxiv · May 14, 2021Cell Biology