Author

C. Offringa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

R. T. Jaspers· 2 shared A. D. Bakker· 1 shared A. Shi· 1 shared F. Le Grand· 1 shared G. Wu· 1 shared J. Jin· 1 shared J. Klein-Nulend· 1 shared K. J. Liu· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPhysiology

R. T. Jaspers

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2 papers

Recent·Most cited

Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism

A. Shi, M. M. G. Hillege, W. Noort, C. Offringa, G. Wu, T. Forouzanfar, W. M. H. Hoogaars, R. C. I. Wüst, R. T. Jaspers

This study shows that myofibre-specific knockout of TGF-β type I receptors in mice increases muscle mass, strength, and mitochondrial activity.

bioRxiv · Aug 30, 2023Physiology

Myofiber stretch induces tensile and shear deformation of muscle stem cells in their native niche

M. Haroon, J. Klein-Nulend, A. D. Bakker, J. Jin, C. Offringa, F. Le Grand, L. Giordani, K. J. Liu, R. D. Knight, R. T. Jaspers

This study shows that muscle stem cells in their native niche experience mechanical deformation from myofiber stretch-shortening and respond with increased nitric oxide production and gene expression related to proliferation.

bioRxiv · Jan 14, 2020Cell Biology