R. T. Jaspers

This study shows that myofibre-specific knockout of TGF-β type I receptors in mice increases muscle mass, strength, and mitochondrial activity.

This study shows miR155 inhibits osteogenesis and reduces bone mass by targeting S1PR1, suggesting miR155 inhibition could promote bone regeneration.

This study shows that muscle stem cells in their native niche experience mechanical deformation from myofiber stretch-shortening and respond with increased nitric oxide production and gene expression related to proliferation.

This study shows that simultaneous knockout of Tgfbr1 and Acvr1b in muscle leads to hypertrophy and enhanced regeneration, but not when only one receptor is knocked out.

This study examines spasticity in mice with a glycine receptor subunit-β deficiency, finding reduced physical performance, growth, and muscle strength, with age-related worsening of symptoms.