Author

W. Noort

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

R. T. Jaspers· 2 shared A. Aharonov· 1 shared A. Shakked· 1 shared A. Shi· 1 shared A. Shoffner· 1 shared A. van Oudenaarden· 1 shared A. Vignaud· 1 shared B. Koopmans· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersPhysiology

R. T. Jaspers

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism

A. Shi, M. M. G. Hillege, W. Noort, C. Offringa, G. Wu, T. Forouzanfar, W. M. H. Hoogaars, R. C. I. Wüst, R. T. Jaspers

This study shows that myofibre-specific knockout of TGF-β type I receptors in mice increases muscle mass, strength, and mitochondrial activity.

bioRxiv · Aug 30, 2023Physiology

Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable Interaction with CTBP2

D. Pastoors, M. Havermans, R. Mulet-Lazaro, D. Brian, W. Noort, J. Grasel, R. Hoogenboezem, L. Smeenk, J. A. Demmers, T. Enver, R. W. Groen, E. Bindels, R. Delwel

This study identifies EVI1's interaction with CTBP1/CTBP2 as critical for AML and shows that inhibiting this interaction can block leukemic growth.

bioRxiv · Jul 11, 2023Cancer Biology

Glycine receptor subunit-β -deficiency in a mouse model of spasticity results in attenuated physical performance, growth and muscle strength

C. Rivares, A. Vignaud, W. Noort, B. Koopmans, M. Loos, M. Kalinichev, R. T. Jaspers

This study examines spasticity in mice with a glycine receptor subunit-β deficiency, finding reduced physical performance, growth, and muscle strength, with age-related worsening of symptoms.

bioRxiv · Jul 15, 2020Physiology

A metabolic switch from OXPHOS to glycolysis is essential for cardiomyocyte proliferation in the regenerating heart

H. Honkoop, D. de Bakker, A. Aharonov, F. Kruse, A. Shakked, P. Nguyen, C. de Heus, L. Garric, M. Muraro, A. Shoffner, F. Tessadori, J. Peterson, W. Noort, G. Posthuma, D. Grun, , J. Bakkers

This study identifies a metabolic switch from OXPHOS to glycolysis in regenerating zebrafish hearts, showing it is essential for cardiomyocyte proliferation and heart regeneration.

bioRxiv · Dec 18, 2018Cell Biology