Proline catabolism is key to facilitating Candida albicans pathogenicity
F. G. S. Silao, T. Jiang, B. Bereczky-Veress, A. Kuehbacher, K. Ryman, N. Uwamohoro, S. Jenull, F. Nogueira, M. Ward, T. Lion, C. F. Urban, S. Rupp, K. Kuchler, C. Chen, C. Peuckert, P. O. Ljungdahl
This study shows that proline catabolism is essential for Candida albicans pathogenicity, as mutations in proline utilization genes reduce virulence in animal models.
bioRxiv · Jan 17, 2023 · PreprintMicrobiology